Manta Devices has developed a number of proprietary pulmonary drug delivery technologies that can be interchangeably combined to meet varying dry powder dose delivery requirements in single or multi dose DPI configurations. Manta's technologies include:

- Blister Opening Technology

- Metering Dose Chamber Technology

- Torus Dispersion Technology

Manta's Blister Opening Technology is enabling and consists of an injection molded cutter that is sealed within a foil on foil dose chamber. The cutting disk opens the foil dose chamber in a clean and consistent manner without dose catch points. In the open position, the cutter integrates with the DPI structure to direct air flow to and from the dose chamber.

Manta's Metering Dose Chamber Technology consists of a dose chamber with its outlet arranged to require air flow exiting the dose chamber to pass through the inlet air flow. This turbulent interaction promotes recirculation and breakdown of larger agglomerates in the dose chamber and provides controlled release of smaller agglomerates that increase efficiency of downstream dispersion engines.

Manta's Torus Dispersion Technology utilizes centrally located air jets to drive air flow and entrained dose around a toroidal chamber. Centripetal force and turbulent air flow causes the dose to deagglomerate against the external chamber walls. Dose metering and dispersion performance can be controlled by varying the air path inlet and outlet sizes. The Torus can perform as a stand alone DPI or can be integrated with other Manta DPI technologies.

Manta's technologies use standard high volume manufacturing materials and processes commonly used in the drug delivery industry. Dose consistency is ensured by the use of factory pre-metered unit doses utilizing standard capsule filling and blister sealing technologies.

Patient compliance is critical to a successful therapeutic outcome and is facilitated by good design and ergonomics. Our delivery platforms are simple to use and require a minimum of user steps to deliver a dose. Our devices are small and convenient and integrate with the user's lifestyle.